专利
专利
 1.     Bruce J. Berne and Ruhong Zhou, Fast methods for simulating biomolecular systems with long-range electrostatic interactions by molecular dynamics, US patent No. 5,915,230, Jun 22, 1999
2.     Ruhong Zhou, Huafeng Xu, Ed Harder, and Bruce J. Berne, System and Method for Molecular Dynamics Simulation , US patent, No. 7,096,167 B2, August 22, 2006
3.     Prasanna Athma, Ajay Royyuru, David Silverman and Ruhong Zhou, Method and apparatus for protein structure analysis, US Patent, No. 7,499,805, March 3, 2009
4.     Ruhong Zhou, David Silverman, Ajay Royyuru, and Prasanna Athma,  Hydrophobic Moment of Multi-domain Proteins, United States, US patent No. 7,877,214, Jan, 25, 2011
5.     Prasanna Athma, Ajay Royyuru, David Silverman, and Ruhong Zhou, Protein structure analysis, US Patent 8,010,297, Aug. 30, 2011
6.     Ruhong Zhou, David Silverman, Ajay Royyuru, and Prasanna Athma, Hydrophobic Moment of Multi-domain Proteins (II), US patent No. 8,010,332, Aug. 30, 2011
7.     Prasanna Athma, Ajay Royyuru, David Silverman, and Ruhong Zhou, Protein structure analysis (II), US Patent 8,386,189, Feb. 26, 2013
8.     Laxmi Parida and Ruhong Zhou, Visual Analysis of a Protein Folding Process, US patent No. 8,423,339, April 16, 2013
9.     James R. Kozloski,   Cliff A. Pickover, Jacinta M.  Wubben, Ruhong Zhou, Association of data to a biological sequence, US Patent No. 9,311,360, April 12, 2016
10.  Binquan Luan and Ruhong Zhou, Nanopore Sensor for Detecting Molecular Interactions, US patent No. 9,372,171, June 21, 2016
11.  Binquan Luan and Ruhong Zhou, DNA/RNA in a Y-shaped Nanochannel, US patent No. 9,428,803, August 30, 2016
12.  Binquan Luan and Ruhong Zhou, DNA/RNA in a Y-shaped Nanochannel (II), US patent No. 9,428,804, August 30, 2016
13.  Binquan Luan and Ruhong Zhou, Base-by-base Ratcheting DNA/RNA in a Y-shaped Nanochannel, US patent No. 9,518,294, Dec. 13, 2016
14.  Binquan Luan and Ruhong Zhou, Base-by-base Ratcheting DNA/RNA in a Y-shaped Nanochannel (II), US patent No. 9,528,153, Dec. 27, 2016
15.  Binquan Luan and Ruhong Zhou, Base-by-base Ratcheting DNA/RNA in a Y-shaped Nanochannel (III), US patent No. 9,534,253, Jan. 3, 2017
16.  Binquan Luan and Ruhong Zhou, Nanopore Device for Drug-like Molecule Screening or Lead Optimization to a Targeted Protein, US patent No. 9,541,541, Jan 10, 2017
17.  Binquan Luan and Ruhong Zhou, Nanopore Sensor for Detecting Molecular Interactions (II), US patent No. 9,588,080, March 7, 2017
18.  Binquan Luan and Ruhong Zhou, Nanopore Sensor for Detecting Molecular Interactions (III), US patent No. 9,995,710, June 12, 2018
19.  Binquan Luan and Ruhong Zhou, Nanopore Sensor for Detecting Molecular Interactions (IV), US patent No. 10,281,428, May 7, 2019
20.  Giacomo Domeniconi, Leili Zhang, Guojing Cong, Chih-Chieh Yang, Ruhong Zhou, Altering protein-ligand structure according to protein-ligand binding affinity, US Patent Pub. 17,065,548, April 14, 2022
21.  Giacomo Domeniconi, Leili Zhang, Guojing Cong, Chih-Chieh Yang, Ruhong Zhou, Optical Flow Based Forecasting of Binding States in Molecular Dynamic Simulations, US Patent Pub. 17,154,120, July 21, 2022


Institute of Quantitative Biology, Zhejiang University
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